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A model of active transcription hubs that unifies the roles of active promoters and enhancers

An essential questions of gene regulation is how large number of enhancers and promoters organize into gene regulatory loops. Using transcription-factor binding enrichment as an indicator of enhancer strength, we identified a portion of H3K27ac peaks as potentially strong enhancers and found a unive...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhu, Iris, Song, Wei, Ovcharenko, Ivan, Landsman, David
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096258/
https://ncbi.nlm.nih.gov/pubmed/33872375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab235
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