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Crystal structure and functional implication of a bacterial cyclic AMP–AMP–GMP synthetase
Mammalian cyclic GMP-AMP synthase (cGAS) and its homologue dinucleotide cyclase in Vibrio cholerae (VcDncV) produce cyclic dinucleotides (CDNs) that participate in the defense against viral infection. Recently, scores of new cGAS/DncV-like nucleotidyltransferases (CD-NTases) were discovered, which p...
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| Udgivet i: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8096243/ https://ncbi.nlm.nih.gov/pubmed/33836064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab165 |
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