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Neuropathology and Neurodegeneration in Rodent Brain Induced by Lentiviral Vectormediated Overexpression of α‐Synuclein

Two mutations in α‐synuclein, the main constituent of Lewy bodies, have been identified in familial Parkinson's disease. We have stereotactically injected lentiviral vectors encoding wild‐type and A30P mutant human α‐synuclein in different brain regions (striatum, substantia nigra, amygdala) of...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Lauwers, Erwin, Debyser, Zeger, Van Dorpe, Jo, De Strooper, Bart, Nuttin, Bart, Baekelandt, Veerle
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095986/
https://ncbi.nlm.nih.gov/pubmed/12946025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2003.tb00035.x
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