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Detection of Ectopic B‐cell Follicles with Germinal Centers in the Meninges of Patients with Secondary Progressive Multiple Sclerosis

Multiple sclerosis (MS) is characterized by synthesis of oligoclonal immunoglobulins and the presence of B‐cell clonal expansions in the central nervous system (CNS). Because ectopic lymphoid tissue generated at sites of chronic inflammation is thought to be important in sustaining immunopathologica...

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Bibliographic Details
Published in:Brain Pathol
Main Authors: Serafini, Barbara, Rosicarelli, Barbara, Magliozzi, Roberta, Stigliano, Egidio, Aloisi, Francesca
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095922/
https://ncbi.nlm.nih.gov/pubmed/15193029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2004.tb00049.x
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