Epstein-Barr Virus-Specific CD8 T Cells Selectively Infiltrate the Brain in Multiple Sclerosis and Interact Locally with Virus-Infected Cells: Clue for a Virus-Driven Immunopathological Mechanism

Epstein-Barr virus (EBV) is a ubiquitous herpesvirus strongly associated with multiple sclerosis (MS), a chronic inflammatory disease of the central nervous system (CNS). However, the mechanisms linking EBV infection to MS pathology are uncertain. Neuropathological and immunological studies suggest...

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Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Serafini, Barbara, Rosicarelli, Barbara, Veroni, Caterina, Mazzola, Gina Adriana, Aloisi, Francesca
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2019
Aiheet:
Pathogenesis and Immunity
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880158/
https://ncbi.nlm.nih.gov/pubmed/31578295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00980-19
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