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Microglial EP2 as a New Target to Increase Amyloid β Phagocytosis and Decrease Amyloid β‐Induced Damage to Neurons

Epidemiologic and animal model data support a role for the prostaglandin pathway in AD pathogenesis. However, unexpected toxicity from protracted use of some nonsteroidal anti‐inflammatory drugs (NSAIDs) compels investigation of therapeutic targets in this pathway other than COX inhibitors. Previous...

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Enregistré dans:
Détails bibliographiques
Publié dans:Brain Pathol
Auteurs principaux: Shie, Feng‐Shiun, Montine, Kathleen S., Breyer, Richard M., Montine, Thomas J.
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095884/
https://ncbi.nlm.nih.gov/pubmed/15912885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2005.tb00509.x
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