Transcriptome-scale spatial gene expression in the human dorsolateral prefrontal cortex

We used the 10x Genomics Visium platform to define the spatial topography of gene expression in the six-layered human dorsolateral prefrontal cortex (DLPFC). We identified extensive layer-enriched expression signatures, and refined associations to previous laminar markers. We overlaid our laminar ex...

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Udgivet i:Nat Neurosci
Main Authors: Maynard, Kristen R., Collado-Torres, Leonardo, Weber, Lukas M., Uytingco, Cedric, Barry, Brianna K., Williams, Stephen R., Catallini, Joseph L., Tran, Matthew N., Besich, Zachary, Tippani, Madhavi, Chew, Jennifer, Yin, Yifeng, Kleinman, Joel E., Hyde, Thomas M., Rao, Nikhil, Hicks, Stephanie C., Martinowich, Keri, Jaffe, Andrew E.
Format: Artigo
Sprog:Inglês
Udgivet: 2021
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095368/
https://ncbi.nlm.nih.gov/pubmed/33558695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-020-00787-0
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