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Switching the Inhibitor‐Enzyme Recognition Profile via Chimeric Carbonic Anhydrase XII
A key part of the optimization of small molecules in pharmaceutical inhibitor development is to vary the molecular design to enhance complementarity of chemical features of the compound with the positioning of amino acids in the active site of a target enzyme. Typically this involves iterations of s...
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| Yayımlandı: | ChemistryOpen |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2021
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8095314/ https://ncbi.nlm.nih.gov/pubmed/33945229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/open.202100042 |
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