A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in mice

SARS-CoV in 2003, SARS-CoV-2 in 2019, and SARS-CoV-2 variants of concern (VOC) can cause deadly infections, underlining the importance of developing broadly effective countermeasures against Group 2B Sarbecoviruses, which could be key in the rapid prevention and mitigation of future zoonotic events....

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Détails bibliographiques
Publié dans:bioRxiv
Auteurs principaux: Martinez, David R., Schaefer, Alexandra, Gobeil, Sophie, Li, Dapeng, De la Cruz, Gabriela, Parks, Robert, Lu, Xiaozhi, Barr, Maggie, Manne, Kartik, Mansouri, Katayoun, Edwards, Robert J., Yount, Boyd, Anasti, Kara, Montgomery, Stephanie A., Shen, Shaunna, Zhou, Tongqing, Kwong, Peter D., Graham, Barney S., Mascola, John R., Montefiori, David. C., Alam, Munir, Sempowski, Gregory D., Wiehe, Kevin, Saunders, Kevin O., Acharya, Priyamvada, Haynes, Barton F., Baric, Ralph S.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095197/
https://ncbi.nlm.nih.gov/pubmed/33948590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.04.27.441655
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