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Absence of the CXCR4 antagonist EPI-X4 from pharmaceutical human serum albumin preparations
BACKGROUND: Endogenous Peptide Inhibitor of CXCR4 (EPI-X4) is a natural antagonist of the CXC chemokine receptor 4 (CXCR4). EPI-X4 is a 16-mer peptide that is released from human serum albumin (HSA) by acidic aspartic proteases such as Cathepsin D and E. Since human serum albumin (HSA) is an importa...
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| Veröffentlicht in: | J Transl Med |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8094565/ https://ncbi.nlm.nih.gov/pubmed/33941197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-021-02859-6 |
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