Loss of the Protein‐Tyrosine Phosphatase DEP‐1/PTPRJ Drives Meningioma Cell Motility

DEP‐1/PTPRJ is a transmembrane protein‐tyrosine phosphatase which has been proposed as a suppressor of epithelial tumors. We have found loss of heterozygosity (LOH) of the PTPRJ gene and loss of DEP‐1 protein expression in a subset of human meningiomas. RNAi‐mediated suppression of DEP‐1 in DEP‐1 po...

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Vydáno v:Brain Pathol
Hlavní autoři: Petermann, Astrid, Haase, Daniela, Wetzel, Andrea, Balavenkatraman, Kamal K., Tenev, Tencho, Gührs, Karl‐Heinz, Friedrich, Sabrina, Nakamura, Makoto, Mawrin, Christian, Böhmer, Frank‐D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2010
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094248/
https://ncbi.nlm.nih.gov/pubmed/21091576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2010.00464.x
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