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Loss of the Protein‐Tyrosine Phosphatase DEP‐1/PTPRJ Drives Meningioma Cell Motility
DEP‐1/PTPRJ is a transmembrane protein‐tyrosine phosphatase which has been proposed as a suppressor of epithelial tumors. We have found loss of heterozygosity (LOH) of the PTPRJ gene and loss of DEP‐1 protein expression in a subset of human meningiomas. RNAi‐mediated suppression of DEP‐1 in DEP‐1 po...
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| Publicado no: | Brain Pathol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8094248/ https://ncbi.nlm.nih.gov/pubmed/21091576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2010.00464.x |
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