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Unraveling the Glioma Epigenome—From Molecular Mechanisms to Novel Biomarkers and Therapeutic Targets

Epigenetic regulation of gene expression by DNA methylation and histone modification is frequently altered in human cancers including gliomas, the most common primary brain tumors. In diffuse astrocytic and oligodendroglial gliomas, epigenetic changes often present as aberrant hypermethylation of 5′...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Malzkorn, Bastian, Wolter, Marietta, Riemenschneider, Markus J., Reifenberger, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094062/
https://ncbi.nlm.nih.gov/pubmed/21939466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2011.00536.x
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