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Unraveling the Glioma Epigenome—From Molecular Mechanisms to Novel Biomarkers and Therapeutic Targets

Epigenetic regulation of gene expression by DNA methylation and histone modification is frequently altered in human cancers including gliomas, the most common primary brain tumors. In diffuse astrocytic and oligodendroglial gliomas, epigenetic changes often present as aberrant hypermethylation of 5′...

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Detalles Bibliográficos
Publicado en:Brain Pathol
Autores principales: Malzkorn, Bastian, Wolter, Marietta, Riemenschneider, Markus J., Reifenberger, Guido
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Publishing Ltd 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094062/
https://ncbi.nlm.nih.gov/pubmed/21939466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2011.00536.x
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