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Alterations in the RB1 Pathway in Low‐grade Diffuse Gliomas Lacking Common Genetic Alterations

We recently reported that the vast majority (>90%) of low‐grade diffuse gliomas (diffuse astrocytoma, oligoastrocytoma and oligodendroglioma) carry at least one of the following genetic alterations: IDH1/2 mutation, TP53 mutation or 1p/19q loss. Only 7% of cases were triple‐negative (ie, lacking...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Kim, Young‐Ho, Lachuer, Joel, Mittelbronn, Michel, Paulus, Werner, Brokinkel, Benjamin, Keyvani, Kathy, Sure, Ulrich, Wrede, Karsten, Nobusawa, Sumihito, Nakazato, Yoichi, Tanaka, Yuko, Vital, Anne, Mariani, Luigi, Ohgaki, Hiroko
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094054/
https://ncbi.nlm.nih.gov/pubmed/21470325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2011.00492.x
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