Frequent BRAF Gain in Low‐Grade Diffuse Gliomas with 1p/19q Loss

Chromosomal 7q34 duplication and BRAF‐KIAA1549 fusion is a characteristic genetic alteration in pilocytic astrocytomas. 7q34 gain appears to be common in diffuse astrocytomas, but its significance is unclear. We assessed BRAF gain and BRAF mutations in 123 low‐grade diffuse gliomas, including 55 dif...

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Vydáno v:Brain Pathol
Hlavní autoři: Kim, Young‐Ho, Nonoguchi, Naosuke, Paulus, Werner, Brokinkel, Benjamin, Keyvani, Kathy, Sure, Ulrich, Wrede, Karsten, Mariani, Luigi, Giangaspero, Felice, Tanaka, Yuko, Nakazato, Yoichi, Vital, Anne, Mittelbronn, Michel, Perry, Arie, Ohgaki, Hiroko
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2012
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8057626/
https://ncbi.nlm.nih.gov/pubmed/22568401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00601.x
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