Frequent BRAF Gain in Low‐Grade Diffuse Gliomas with 1p/19q Loss

Chromosomal 7q34 duplication and BRAF‐KIAA1549 fusion is a characteristic genetic alteration in pilocytic astrocytomas. 7q34 gain appears to be common in diffuse astrocytomas, but its significance is unclear. We assessed BRAF gain and BRAF mutations in 123 low‐grade diffuse gliomas, including 55 dif...

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Dades bibliogràfiques
Publicat a:Brain Pathol
Autors principals: Kim, Young‐Ho, Nonoguchi, Naosuke, Paulus, Werner, Brokinkel, Benjamin, Keyvani, Kathy, Sure, Ulrich, Wrede, Karsten, Mariani, Luigi, Giangaspero, Felice, Tanaka, Yuko, Nakazato, Yoichi, Vital, Anne, Mittelbronn, Michel, Perry, Arie, Ohgaki, Hiroko
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2012
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8057626/
https://ncbi.nlm.nih.gov/pubmed/22568401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00601.x
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