Frequent BRAF Gain in Low‐Grade Diffuse Gliomas with 1p/19q Loss

Chromosomal 7q34 duplication and BRAF‐KIAA1549 fusion is a characteristic genetic alteration in pilocytic astrocytomas. 7q34 gain appears to be common in diffuse astrocytomas, but its significance is unclear. We assessed BRAF gain and BRAF mutations in 123 low‐grade diffuse gliomas, including 55 dif...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Kim, Young‐Ho, Nonoguchi, Naosuke, Paulus, Werner, Brokinkel, Benjamin, Keyvani, Kathy, Sure, Ulrich, Wrede, Karsten, Mariani, Luigi, Giangaspero, Felice, Tanaka, Yuko, Nakazato, Yoichi, Vital, Anne, Mittelbronn, Michel, Perry, Arie, Ohgaki, Hiroko
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8057626/
https://ncbi.nlm.nih.gov/pubmed/22568401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2012.00601.x
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