Clozapine Metabolism is Associated With Absolute Neutrophil Count in Individuals With Treatment-Resistant Schizophrenia

Up to one-third of those with schizophrenia fail to respond to standard antipsychotics and are considered to have treatment-resistant schizophrenia, a condition for which clozapine is the only evidence-based medication. While up to 60% of treated individuals obtain therapeutic benefits from clozapin...

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Bibliografiske detaljer
Udgivet i:Front Pharmacol
Main Authors: Willcocks, Isabella R., Legge, Sophie E., Nalmpanti, Mariana, Mazzeo, Lucy, King, Adrian, Jansen, John, Helthuis, Marinka, Owen, Michael J., O’Donovan, Michael C., Walters, James T. R., Pardiñas, Antonio F.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8094024/
https://ncbi.nlm.nih.gov/pubmed/33959025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.658734
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