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Clozapine and desmethylclozapine: correlation with neutrophils and leucocytes counting in Mexican patients with schizophrenia

PURPOSE: The aim of present study is to measure plasma clozapine (CLZ) and N-desmethyl clozapine (DMC) as biomarkers to correlate drug concentrations with the appearance of preclinical adverse hematic effects. METHODS: A high-performance liquid chromatographic method, using a diode-array (ultraviole...

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Detalhes bibliográficos
Publicado no:BMC Psychiatry
Main Authors: Vaquero-Baez, Mayela, Díaz-Ruíz, Araceli, Tristán-López, Luis, Aviña-Cervantes, Carlos, Torner, Carlos, Ramírez-Bermúdez, Jesús, Montes, Sergio, Ríos, Camilo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785871/
https://ncbi.nlm.nih.gov/pubmed/31597566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12888-019-2286-1
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