Berberine Regulated miR150-5p to Inhibit P2X7 Receptor, EMMPRIN and MMP-9 Expression in oxLDL Induced Macrophages

Elevated extracellular matrix metalloproteinase inducer (EMMPRIN) and matrix metalloproteinase-9 (MMP-9) in oxidized low density lipoprotein (oxLDL)-induced macrophages leads to the progression of vulnerable plaques by degradation of the extracellular matrix. Our previous report showed that berberin...

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Publicat a:Front Pharmacol
Autors principals: Lu, Lin, Huang, Jianjian, Xue, Xia, Wang, Ting, Huang, Zhouqing, Li, Jianmin
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093865/
https://ncbi.nlm.nih.gov/pubmed/33959010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.639558
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