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CYP2D6 Genetic Variation and Its Implication for Vivax Malaria Treatment in Madagascar

Plasmodium vivax is one of the five human malaria parasite species, which has a wide geographical distribution and can cause severe disease and fatal outcomes. It has the ability to relapse from dormant liver stages (hypnozoites), weeks to months after clearance of the acute blood-stage infection. A...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Mehlotra, Rajeev K., Gaedigk, Andrea, Howes, Rosalind E., Rakotomanga, Tovonahary A., Ratsimbasoa, Arsene C., Zimmerman, Peter A.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093859/
https://ncbi.nlm.nih.gov/pubmed/33959023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.654054
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