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Xanthohumol ameliorates Diet-Induced Liver Dysfunction via Farnesoid X Receptor-Dependent and Independent Signaling

The farnesoid X receptor (FXR) plays a critical role in the regulation of lipid and bile acid (BA) homeostasis. Hepatic FXR loss results in lipid and BA accumulation, and progression from hepatic steatosis to nonalcoholic steatohepatitis (NASH). This study aimed to evaluate the effects of xanthohumo...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Paraiso, Ines L., Tran, Thai Q., Magana, Armando Alcazar, Kundu, Payel, Choi, Jaewoo, Maier, Claudia S., Bobe, Gerd, Raber, Jacob, Kioussi, Chrissa, Stevens, Jan F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093804/
https://ncbi.nlm.nih.gov/pubmed/33959012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.643857
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