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STAT5 Regulation of Sex-Dependent Hepatic CpG Methylation at Distal Regulatory Elements Mapping to Sex-Biased Genes

Growth hormone-activated STAT5b is an essential regulator of sex-differential gene expression in mouse liver; however, its impact on hepatic gene expression and epigenetic responses is poorly understood. Here, we found a substantial, albeit incomplete loss of liver sex bias in hepatocyte-specific ST...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Main Authors: Hao, Pengying, Waxman, David J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093489/
https://ncbi.nlm.nih.gov/pubmed/33199496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00166-20
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