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RNAi targeting heparin cofactor II promotes hemostasis in hemophilia A

Hemophilia A is a hemorrhagic disease due to congenital deficiencies of coagulation factor VIII (FVIII). Studies show that hemophilia patients with anticoagulant deficiency present less severe hemorrhagic phenotypes. We aimed to find a new therapeutic option for hemophilia patients by RNA interferen...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Lin, Wen-yi, Zhu, Ruiqi, Zhang, Zhen, Lu, Xuan, Wang, Huafang, He, Wenjuan, Hu, Yu, Tang, Liang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093307/
https://ncbi.nlm.nih.gov/pubmed/33996250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2021.03.022
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