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Pharmacokinetics and Pharmacodynamics of High-Dose Piperacillin–Tazobactam in Obese Patients

BACKGROUND AND OBJECTIVE: Standard piperacillin–tazobactam (P-T) dosing may be suboptimal in obesity, but high-dose regimens have not been studied. We prospectively evaluated the pharmacokinetics and pharmacodynamics of standard- and high-dose P-T in obese adult inpatients. METHODS: Those receiving...

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書目詳細資料
發表在:Eur J Drug Metab Pharmacokinet
Main Authors: Veillette, John J., Winans, S. Alexander, Maskiewicz, Victoria K., Truong, James, Jones, Ronald N., Forland, Steven C.
格式: Artigo
語言:Inglês
出版: Springer International Publishing 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8093170/
https://ncbi.nlm.nih.gov/pubmed/33743171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13318-021-00677-1
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