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Impact of Bicarbonate on PBP2a Production, Maturation, and Functionality in Methicillin-Resistant Staphylococcus aureus
Certain methicillin-resistant Staphylococcus aureus (MRSA) strains exhibit β-lactam susceptibility in vitro, ex vivo, and in vivo in the presence of NaHCO(3) (NaHCO(3)-responsive MRSA). Here, we investigate the impact of NaHCO(3) on factors required for PBP2a functionality. Prototype NaHCO(3)-respon...
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| Veröffentlicht in: | Antimicrob Agents Chemother |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8092911/ https://ncbi.nlm.nih.gov/pubmed/33649115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02621-20 |
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