Impact of Bicarbonate on PBP2a Production, Maturation, and Functionality in Methicillin-Resistant Staphylococcus aureus

Certain methicillin-resistant Staphylococcus aureus (MRSA) strains exhibit β-lactam susceptibility in vitro, ex vivo, and in vivo in the presence of NaHCO(3) (NaHCO(3)-responsive MRSA). Here, we investigate the impact of NaHCO(3) on factors required for PBP2a functionality. Prototype NaHCO(3)-respon...

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Publicat a:Antimicrob Agents Chemother
Autors principals: Ersoy, Selvi C., Chambers, Henry F., Proctor, Richard A., Rosato, Adriana E., Mishra, Nagendra N., Xiong, Yan Q., Bayer, Arnold S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Susceptibility
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092911/
https://ncbi.nlm.nih.gov/pubmed/33649115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02621-20
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