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Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Biapenem in Healthy Adult Subjects
The pharmacokinetics and safety of biapenem were studied in 36 healthy adult subjects in a randomized, placebo-controlled, double blind, sequential single- and multiple-ascending-dose study using doses from 250 to 1,250 mg administered three times a day using 3-h infusions. Maximum concentrations fo...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8092883/ https://ncbi.nlm.nih.gov/pubmed/33685898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02612-20 |
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