Identification of Two Critical Neutralizing Epitopes in the Receptor Binding Domain of Hepatitis B Virus preS1

Hepatitis B virus (HBV) infection is a major public health problem. Human hepatocytes are infected with HBV via binding between the preS1 region in the large envelope protein of HBV and sodium taurocholate cotransporting polypeptide. Although several monoclonal antibodies (MAbs) that recognize the r...

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Bibliographic Details
Published in:J Virol
Main Authors: Yato, Keigo, Onodera, Taishi, Matsuda, Mami, Moriyama, Saya, Fujimoto, Akira, Watashi, Koichi, Aizaki, Hideki, Tanaka, Tomohisa, Moriishi, Kohji, Nishitsuji, Hironori, Shimotohno, Kunitada, Tamura, Koji, Takahashi, Yoshimasa, Wakita, Takaji, Muramatsu, Masamichi, Kato, Takanobu, Suzuki, Ryosuke
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092832/
https://ncbi.nlm.nih.gov/pubmed/33298539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01680-20
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