Development of a cell-based assay to identify hepatitis B virus entry inhibitors targeting the sodium taurocholate cotransporting polypeptide

Sodium taurocholate cotransporting polypeptide (NTCP) is a major entry receptor of hepatitis B virus (HBV) and one of the most attractive targets for anti-HBV drugs. We developed a cell-mediated drug screening method to monitor NTCP expression on the cell surface by generating a HepG2 cell line with...

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Udgivet i:Oncotarget
Main Authors: Miyakawa, Kei, Matsunaga, Satoko, Yamaoka, Yutaro, Dairaku, Mina, Fukano, Kento, Kimura, Hirokazu, Chimuro, Tomoyuki, Nishitsuji, Hironori, Watashi, Koichi, Shimotohno, Kunitada, Wakita, Takaji, Ryo, Akihide
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5955094/
https://ncbi.nlm.nih.gov/pubmed/29805766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25348
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