The Internal Ribosome Entry Site of Dengue Virus mRNA Is Active When Cap-Dependent Translation Initiation Is Inhibited

Dengue virus (DENV) is an enveloped, positive-sense, single-stranded RNA virus belonging to the Flaviviridae family. Translation initiation of DENV mRNA can occur by a cap-dependent or a cap-independent mechanism. Two non-mutually exclusive cap-independent mechanisms of translation initiation have b...

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Bibliographic Details
Published in:J Virol
Main Authors: Fernández-García, Leandro, Angulo, Jenniffer, Ramos, Hade, Barrera, Aldo, Pino, Karla, Vera-Otarola, Jorge, López-Lastra, Marcelo
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2021
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092825/
https://ncbi.nlm.nih.gov/pubmed/33298544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01998-20
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