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Platinum(II) N-heterocyclic carbene complexes arrest metastatic tumor growth
Vimentin is a cytoskeletal intermediate filament protein that plays pivotal roles in tumor initiation, progression, and metastasis, and its overexpression in aggressive cancers predicted poor prognosis. Herein described is a highly effective antitumor and antimetastatic metal complex [Pt(II)(C^N^N)(...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8092596/ https://ncbi.nlm.nih.gov/pubmed/33883283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2025806118 |
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