Luminescent platinum(II) complexes with functionalized N-heterocyclic carbene or diphosphine selectively probe mismatched and abasic DNA

The selective targeting of mismatched DNA overexpressed in cancer cells is an appealing strategy in designing cancer diagnosis and therapy protocols. Few luminescent probes that specifically detect intracellular mismatched DNA have been reported. Here we used Pt(II) complexes with luminescence sensi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Fung, Sin Ki, Zou, Taotao, Cao, Bei, Chen, Tianfeng, To, Wai-Pong, Yang, Chen, Lok, Chun-Nam, Che, Chi-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4757794/
https://ncbi.nlm.nih.gov/pubmed/26883164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10655
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