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Screening and Identification of Metacaspase Inhibitors: Evaluation of Inhibition Mechanism and Trypanocidal Activity

A common strategy to identify new antiparasitic agents is the targeting of proteases, due to their essential contributions to parasite growth and development. Metacaspases (MCAs) are cysteine proteases present in fungi, protozoa, and plants. These enzymes, which are associated with crucial cellular...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Pérez, Brian, Bouvier, León A., Cazzulo, Juan José, Agüero, Fernán, Salas-Sarduy, Emir, Alvarez, Vanina E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092552/
https://ncbi.nlm.nih.gov/pubmed/33318019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01330-20
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