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Screening and Identification of Metacaspase Inhibitors: Evaluation of Inhibition Mechanism and Trypanocidal Activity

A common strategy to identify new antiparasitic agents is the targeting of proteases, due to their essential contributions to parasite growth and development. Metacaspases (MCAs) are cysteine proteases present in fungi, protozoa, and plants. These enzymes, which are associated with crucial cellular...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Main Authors: Pérez, Brian, Bouvier, León A., Cazzulo, Juan José, Agüero, Fernán, Salas-Sarduy, Emir, Alvarez, Vanina E.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092552/
https://ncbi.nlm.nih.gov/pubmed/33318019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01330-20
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