Multiple Single-Nucleotide Polymorphism Detection for Antimalarial Pyrimethamine Resistance via Allele-Specific PCR Coupled with Gold Nanoparticle-Based Lateral Flow Biosensor

Molecular genotyping holds tremendous potential to detect antimalarial drug resistance (ADR) related to single nucleotide polymorphisms (SNPs). However, it relies on the use of complicated procedures and expensive instruments. Thus, rapid point-of-care testing (POCT) molecular tools are urgently nee...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Jiang, Tingting, Huang, Yan, Cheng, Weijia, Sun, Yifei, Wei, Wei, Wu, Kai, Shen, Chen, Fu, Xiaolong, Dong, Haifeng, Li, Jian
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Analytical Procedures
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092547/
https://ncbi.nlm.nih.gov/pubmed/33361302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01063-20
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