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Multiple Single-Nucleotide Polymorphism Detection for Antimalarial Pyrimethamine Resistance via Allele-Specific PCR Coupled with Gold Nanoparticle-Based Lateral Flow Biosensor

Molecular genotyping holds tremendous potential to detect antimalarial drug resistance (ADR) related to single nucleotide polymorphisms (SNPs). However, it relies on the use of complicated procedures and expensive instruments. Thus, rapid point-of-care testing (POCT) molecular tools are urgently nee...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Jiang, Tingting, Huang, Yan, Cheng, Weijia, Sun, Yifei, Wei, Wei, Wu, Kai, Shen, Chen, Fu, Xiaolong, Dong, Haifeng, Li, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092547/
https://ncbi.nlm.nih.gov/pubmed/33361302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01063-20
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