Efficacy of a Cap-Dependent Endonuclease Inhibitor and Neuraminidase Inhibitors against H7N9 Highly Pathogenic Avian Influenza Virus Causing Severe Viral Pneumonia in Cynomolgus Macaques

H7N9 highly pathogenic avian influenza virus (HPAIV) infection in a human was first reported in 2017. A/duck/Japan/AQ-HE29-22/2017 (H7N9) (Dk/HE29-22), found in imported duck meat at an airport in Japan, possesses a hemagglutinin with a multibasic cleavage site, indicating high pathogenicity in chic...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Suzuki, Saori, Nguyen, Cong Thanh, Ogata-Nakahara, Ayako, Shibata, Akihiro, Osaka, Hiroyuki, Ishigaki, Hirohito, Okamatsu, Masatoshi, Sakoda, Yoshihiro, Kida, Hiroshi, Ogasawara, Kazumasa, Itoh, Yasushi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2021
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092539/
https://ncbi.nlm.nih.gov/pubmed/33257455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01825-20
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