Emergence of H7N9 Influenza A Virus Resistant to Neuraminidase Inhibitors in Nonhuman Primates

The number of patients infected with H7N9 influenza virus has been increasing since 2013. We examined the efficacy of neuraminidase (NA) inhibitors and the efficacy of a vaccine against an H7N9 influenza virus, A/Anhui/1/2013 (H7N9), isolated from a patient in a cynomolgus macaque model. NA inhibito...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Itoh, Yasushi, Shichinohe, Shintaro, Nakayama, Misako, Igarashi, Manabu, Ishii, Akihiro, Ishigaki, Hirohito, Ishida, Hideaki, Kitagawa, Naoko, Sasamura, Takako, Shiohara, Masanori, Doi, Michiko, Tsuchiya, Hideaki, Nakamura, Shinichiro, Okamatsu, Masatoshi, Sakoda, Yoshihiro, Kida, Hiroshi, Ogasawara, Kazumasa
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505273/
https://ncbi.nlm.nih.gov/pubmed/26055368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00793-15
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