Chitinase 3-like 1 is a profibrogenic factor overexpressed in the aging liver and in patients with liver cirrhosis

Older age at the time of infection with hepatitis viruses is associated with an increased risk of liver fibrosis progression. We hypothesized that the pace of fibrosis progression may reflect changes in gene expression within the aging liver. We compared gene expression in liver specimens from 54 ad...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Nishimura, Norihisa, De Battista, Davide, McGivern, David R., Engle, Ronald E., Tice, Ashley, Fares-Gusmao, Rafaelle, Kabat, Juraj, Pomerenke, Anna, Nguyen, Hanh, Sato, Shinya, Bock, Kevin W., Moore, Ian N., Kleiner, David E., Zamboni, Fausto, Alter, Harvey J., Govindarajan, Sugantha, Farci, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092404/
https://ncbi.nlm.nih.gov/pubmed/33888584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2019633118
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