Multidisciplinary Approaches Identify Compounds that Bind to Human ACE2 or SARS-CoV-2 Spike Protein as Candidates to Block SARS-CoV-2–ACE2 Receptor Interactions

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a recently emerged virus that causes coronavirus infectious disease 2019 (COVID-19). SARS-CoV-2 spike protein, like SARS-CoV-1, uses the angiotensin converting enzyme 2 (ACE2) as a cellular receptor to initiate infection. Compounds that...

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Pubblicato in:mBio
Autori principali: Day, Christopher J., Bailly, Benjamin, Guillon, Patrice, Dirr, Larissa, Jen, Freda E.-C., Spillings, Belinda L., Mak, Johnson, von Itzstein, Mark, Haselhorst, Thomas, Jennings, Michael P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092326/
https://ncbi.nlm.nih.gov/pubmed/33785634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03681-20
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