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Queuine Is a Nutritional Regulator of Entamoeba histolytica Response to Oxidative Stress and a Virulence Attenuator

Queuosine is a naturally occurring modified ribonucleoside found in the first position of the anticodon of the transfer RNAs for Asp, Asn, His, and Tyr. Eukaryotes lack pathways to synthesize queuine, the nucleobase precursor to queuosine, and must obtain it from diet or gut microbiota. Here, we des...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Nagaraja, Shruti, Cai, Maggi W., Sun, Jingjing, Varet, Hugo, Sarid, Lotem, Trebicz-Geffen, Meirav, Shaulov, Yana, Mazumdar, Mohit, Legendre, Rachel, Coppée, Jean-Yves, Begley, Thomas J., Dedon, Peter C., Gourinath, Samudrala, Guillen, Nancy, Saito-Nakano, Yumiko, Shimokawa, Chikako, Hisaeda, Hajime, Ankri, Serge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092309/
https://ncbi.nlm.nih.gov/pubmed/33688012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03549-20
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