Queuine Is a Nutritional Regulator of Entamoeba histolytica Response to Oxidative Stress and a Virulence Attenuator

Queuosine is a naturally occurring modified ribonucleoside found in the first position of the anticodon of the transfer RNAs for Asp, Asn, His, and Tyr. Eukaryotes lack pathways to synthesize queuine, the nucleobase precursor to queuosine, and must obtain it from diet or gut microbiota. Here, we des...

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Veröffentlicht in:mBio
Hauptverfasser: Nagaraja, Shruti, Cai, Maggi W., Sun, Jingjing, Varet, Hugo, Sarid, Lotem, Trebicz-Geffen, Meirav, Shaulov, Yana, Mazumdar, Mohit, Legendre, Rachel, Coppée, Jean-Yves, Begley, Thomas J., Dedon, Peter C., Gourinath, Samudrala, Guillen, Nancy, Saito-Nakano, Yumiko, Shimokawa, Chikako, Hisaeda, Hajime, Ankri, Serge
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092309/
https://ncbi.nlm.nih.gov/pubmed/33688012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.03549-20
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