Extent of Cytomegalovirus Replication in the Human Host Depends on Variations of the HLA-E/UL40 Axis

Human cytomegalovirus (HCMV) may cause severe infections in lung transplant recipients (LTRs). In response to HCMV infections, a subset of NKG2C(+) NK cells expands, which limits HCMV replication and is characterized by high expression of the activating NKG2C/CD94 and absence of the inhibitory NKG2A...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Vietzen, Hannes, Rückert, Timo, Hartenberger, Svenja, Honsig, Claudia, Jaksch, Peter, Geleff, Silvana, Hammer, Quirin, Romagnani, Chiara, Segura-Wang, Maia, Puchhammer-Stöckl, Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092275/
https://ncbi.nlm.nih.gov/pubmed/33727352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02996-20
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