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Human Cytomegalovirus miR-US25-1 Targets the GTPase RhoA To Inhibit CD34(+) Hematopoietic Progenitor Cell Proliferation To Maintain the Latent Viral Genome
Human cytomegalovirus (HCMV) microRNAs play essential roles in latency and reactivation in CD34(+) hematopoietic progenitor cells (HPCs) via regulation of viral and cellular gene expression. In the present study, we show that HCMV miR-US25-1 targets RhoA, a small GTPase required for CD34(+) HPC self...
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| 出版年: | mBio |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2021
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8092260/ https://ncbi.nlm.nih.gov/pubmed/33824207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00621-21 |
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