SARS-CoV-2 ORF6 Disrupts Bidirectional Nucleocytoplasmic Transport through Interactions with Rae1 and Nup98

RNA viruses that replicate in the cytoplasm often disrupt nucleocytoplasmic transport to preferentially translate their own transcripts and prevent host antiviral responses. The Sarbecovirus accessory protein ORF6 has previously been shown to be a major inhibitor of interferon production in both sev...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Addetia, Amin, Lieberman, Nicole A. P., Phung, Quynh, Hsiang, Tien-Ying, Xie, Hong, Roychoudhury, Pavitra, Shrestha, Lasata, Loprieno, Michelle A., Huang, Meei-Li, Gale, Michael, Jerome, Keith R., Greninger, Alexander L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092196/
https://ncbi.nlm.nih.gov/pubmed/33849972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00065-21
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