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Downregulation of both mismatch repair and non-homologous end-joining pathways in hypoxic brain tumour cell lines
Glioblastoma, a grade IV astrocytoma, has a poor survival rate in part due to ineffective treatment options available. These tumours are heterogeneous with areas of low oxygen levels, termed hypoxic regions. Many intra-cellular signalling pathways, including DNA repair, can be altered by hypoxia. Si...
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| 發表在: | PeerJ |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
PeerJ Inc.
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8092103/ https://ncbi.nlm.nih.gov/pubmed/33986995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.11275 |
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