Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands

Massively parallel reporter assays (MPRAs) are useful tools to characterize regulatory elements in human genomes. An aspect of MPRAs that is not typically the focus of analysis is their intrinsic ability to differentiate activity levels for a given sequence element when placed in both of its possibl...

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Bibliografiske detaljer
Udgivet i:Genome Res
Main Authors: Roberts, Brian S., Partridge, E. Christopher, Moyers, Bryan A., Agarwal, Vikram, Newberry, Kimberly M., Martin, Beth K., Shendure, Jay, Myers, Richard M., Cooper, Gregory M.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092006/
https://ncbi.nlm.nih.gov/pubmed/33879525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.270751.120
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