Genome-wide strand asymmetry in massively parallel reporter activity favors genic strands

Massively parallel reporter assays (MPRAs) are useful tools to characterize regulatory elements in human genomes. An aspect of MPRAs that is not typically the focus of analysis is their intrinsic ability to differentiate activity levels for a given sequence element when placed in both of its possibl...

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Bibliographische Detailangaben
Veröffentlicht in:Genome Res
Hauptverfasser: Roberts, Brian S., Partridge, E. Christopher, Moyers, Bryan A., Agarwal, Vikram, Newberry, Kimberly M., Martin, Beth K., Shendure, Jay, Myers, Richard M., Cooper, Gregory M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8092006/
https://ncbi.nlm.nih.gov/pubmed/33879525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.270751.120
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