Critical roles of transcriptional coactivator MED1 in the formation and function of mouse adipose tissues

The MED1 subunit has been shown to mediate ligand-dependent binding of the Mediator coactivator complex to multiple nuclear receptors, including the adipogenic PPARγ, and to play an essential role in ectopic PPARγ-induced adipogenesis of mouse embryonic fibroblasts. However, the precise roles of MED...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Ito, Keiichi, Schneeberger, Marc, Gerber, Alan, Jishage, Miki, Marchildon, Francois, Maganti, Aarthi V., Cohen, Paul, Friedman, Jeffrey M., Roeder, Robert G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2021
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091968/
https://ncbi.nlm.nih.gov/pubmed/33888560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.346791.120
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