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Modeling human hepatic steatosis in pluripotent stem cell-derived hepatocytes
This protocol describes the production of hepatocyte-like cells (HLCs) from human pluripotent stem cells and how to induce hepatic steatosis, a condition characterized by intracellular lipid accumulation. Following differentiation to an HLC phenotype, intracellular lipid accumulation is induced with...
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| Publié dans: | STAR Protoc |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Elsevier
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8091923/ https://ncbi.nlm.nih.gov/pubmed/33997813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100493 |
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