Neurotoxic reactive astrocytes drive neuronal death following retinal injury

Glaucoma is a neurodegenerative disease that features the death of retinal ganglion cells (RGCs) in the retina, often as a result of prolonged increases in intraocular pressure. We show that preventing the formation of neuroinflammatory reactive astrocytes prevents the death of RGCs normally seen in...

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Udgivet i:Cell Rep
Main Authors: Guttenplan, Kevin A., Stafford, Benjamin K., El-Danaf, Rana N., Adler, Drew I., Münch, Alexandra E., Weigel, Maya K., Huberman, Andrew D., Liddelow, Shane A.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091906/
https://ncbi.nlm.nih.gov/pubmed/32579912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107776
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