SREBP1/FASN/cholesterol axis facilitates radioresistance in colorectal cancer

Acquired and intrinsic radioresistance remains a major challenge during the treatment of patients with colorectal cancer (CRC). Aberrant cholesterol metabolism precipitates the development of multiple cancers. Here, we report that exogenous or endogenous cholesterol enhances the radioresistance of C...

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Veröffentlicht in:FEBS Open Bio
Hauptverfasser: Jin, Yuxiao, Chen, Zhiyuan, Dong, Jiali, Wang, Bin, Fan, Saijun, Yang, Xiaodong, Cui, Ming
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091817/
https://ncbi.nlm.nih.gov/pubmed/33665967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.13137
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